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Fluvoxamine stimulates oligodendrogenesis of cultured neural stem cells and attenuates inflammation and demyelination in an animal model of multiple sclerosis

Multiple Sclerosis (MS) require medications controlling severity of the pathology and depression, affecting more than half of the patients. In this study, the effect of antidepressant drug fluvoxamine, a selective serotonin reuptake inhibitor, was investigated in vitro and in vivo. Nanomolar concent...

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Detalles Bibliográficos
Autores principales: Ghareghani, Majid, Zibara, Kazem, Sadeghi, Heibatollah, Dokoohaki, Shima, Sadeghi, Hossein, Aryanpour, Roya, Ghanbari, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501834/
https://www.ncbi.nlm.nih.gov/pubmed/28687730
http://dx.doi.org/10.1038/s41598-017-04968-z