X-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine γ-lyase

Pyridoxal 5′-phosphate (PLP)-enzymes are essentially involved in amino acid and amine metabolism of a wide variety of organisms. Despite their extensive biochemical studies, there are little evidence and structural data to comprehensively elaborate the catalytic mechanism. We obtained X-ray snapshot...

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Detalles Bibliográficos
Autores principales: Sato, Dan, Shiba, Tomoo, Karaki, Tsuyoshi, Yamagata, Wataru, Nozaki, Tomoyoshi, Nakazawa, Takashi, Harada, Shigeharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501846/
https://www.ncbi.nlm.nih.gov/pubmed/28687762
http://dx.doi.org/10.1038/s41598-017-05032-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501846/
https://www.ncbi.nlm.nih.gov/pubmed/28687762
http://dx.doi.org/10.1038/s41598-017-05032-6

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