PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory

Lysine-specific demethylase 1 (LSD1) is a histone demethylase that participates in transcriptional repression or activation. Recent studies reported that LSD1 is involved in learning and memory. Although LSD1 phosphorylation by PKCα was implicated in circadian rhythmicity, the importance of LSD1 pho...

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Detalles Bibliográficos
Autores principales: Lim, Chae-Seok, Nam, Hye Jin, Lee, Jaehyun, Kim, Dongha, Choi, Ja Eun, Kang, SukJae Joshua, Kim, Somi, Kim, Hyopil, Kwak, Chuljung, Shim, Kyu-Won, Kim, Siyong, Ko, Hyoung-Gon, Lee, Ro Un, Jang, Eun-Hae, Yoo, Juyoun, Shim, Jaehoon, Islam, Md Ariful, Lee, Yong-Seok, Lee, Jae-Hyung, Baek, Sung Hee, Kaang, Bong-Kiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501860/
https://www.ncbi.nlm.nih.gov/pubmed/28687800
http://dx.doi.org/10.1038/s41598-017-05239-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501860/
https://www.ncbi.nlm.nih.gov/pubmed/28687800
http://dx.doi.org/10.1038/s41598-017-05239-7

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