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PKCα-mediated phosphorylation of LSD1 is required for presynaptic plasticity and hippocampal learning and memory
Lysine-specific demethylase 1 (LSD1) is a histone demethylase that participates in transcriptional repression or activation. Recent studies reported that LSD1 is involved in learning and memory. Although LSD1 phosphorylation by PKCα was implicated in circadian rhythmicity, the importance of LSD1 pho...
Autores principales: | Lim, Chae-Seok, Nam, Hye Jin, Lee, Jaehyun, Kim, Dongha, Choi, Ja Eun, Kang, SukJae Joshua, Kim, Somi, Kim, Hyopil, Kwak, Chuljung, Shim, Kyu-Won, Kim, Siyong, Ko, Hyoung-Gon, Lee, Ro Un, Jang, Eun-Hae, Yoo, Juyoun, Shim, Jaehoon, Islam, Md Ariful, Lee, Yong-Seok, Lee, Jae-Hyung, Baek, Sung Hee, Kaang, Bong-Kiun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501860/ https://www.ncbi.nlm.nih.gov/pubmed/28687800 http://dx.doi.org/10.1038/s41598-017-05239-7 |
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