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Effect of everolimus on the glucose metabolic pathway in mouse skeletal muscle cells (C2C12)

INTRODUCTION: Everolimus selectively inhibits mammalian target of rapamycin complex 1 (mTORC1) and exerts an antineoplastic effect. Metabolic disturbance has emerged as a common and unique side effect of everolimus. OBJECTIVES: We used targeted metabolomic analysis to investigate the effects of ever...

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Detalles Bibliográficos
Autores principales: Yoshida, Kayoko, Imamura, Chiyo K., Hara, Kanako, Mochizuki, Mayumi, Tanigawara, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501892/
https://www.ncbi.nlm.nih.gov/pubmed/28781589
http://dx.doi.org/10.1007/s11306-017-1236-5