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Regulation of early growth response 2 expression by secreted frizzled related protein 1

BACKGROUND: Secreted frizzled-related protein 1 (SFRP1) expression is down-regulated in a multitude of cancers, including breast cancer. Loss of Sfrp1 also exacerbates weight gain as well as inflammation. Additionally, loss of SFRP1 enhances TGF-β signaling and the downstream MAPK pathway. TGF-β has...

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Detalles Bibliográficos
Autores principales:	Gregory, Kelly J., Morin, Stephanie M., Schneider, Sallie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501954/ https://www.ncbi.nlm.nih.gov/pubmed/28687085 http://dx.doi.org/10.1186/s12885-017-3426-y

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