Insufficient antibody validation challenges oestrogen receptor beta research

The discovery of oestrogen receptor β (ERβ/ESR2) was a landmark discovery. Its reported expression and homology with breast cancer pharmacological target ERα (ESR1) raised hopes for improved endocrine therapies. After 20 years of intense research, this has not materialized. We here perform a rigorou...

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Detalles Bibliográficos
Autores principales: Andersson, Sandra, Sundberg, Mårten, Pristovsek, Nusa, Ibrahim, Ahmed, Jonsson, Philip, Katona, Borbala, Clausson, Carl-Magnus, Zieba, Agata, Ramström, Margareta, Söderberg, Ola, Williams, Cecilia, Asplund, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501969/
https://www.ncbi.nlm.nih.gov/pubmed/28643774
http://dx.doi.org/10.1038/ncomms15840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501969/
https://www.ncbi.nlm.nih.gov/pubmed/28643774
http://dx.doi.org/10.1038/ncomms15840

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