Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities

Metformin is a commonly prescribed type II diabetes medication that exhibits promising anticancer effects. Recently, these effects were found to be associated, at least in part, with a modulation of microRNA expression. However, the mechanisms by which single modulated microRNAs mediate the anticanc...

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Detalles Bibliográficos
Autores principales: Pulito, Claudio, Mori, Federica, Sacconi, Andrea, Goeman, Frauke, Ferraiuolo, Maria, Pasanisi, Patrizia, Campagnoli, Carlo, Berrino, Franco, Fanciulli, Maurizio, Ford, Rebecca J, Levrero, Massimo, Pediconi, Natalia, Ciuffreda, Ludovica, Milella, Michele, Steinberg, Gregory R, Cioce, Mario, Muti, Paola, Strano, Sabrina, Blandino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501975/
https://www.ncbi.nlm.nih.gov/pubmed/28698800
http://dx.doi.org/10.1038/celldisc.2017.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501975/
https://www.ncbi.nlm.nih.gov/pubmed/28698800
http://dx.doi.org/10.1038/celldisc.2017.22

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