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Downregulation of Smac attenuates H(2)O(2)-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells
BACKGROUND: Second mitochondria-derived activator of caspases (Smac) is reported to promote apoptosis. Given the important role of apoptosis in cataract development, the aim of this study was to investigate whether Smac induces human lens epithelial cell (HLEC) apoptosis via endoplasmic reticulum st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502174/ https://www.ncbi.nlm.nih.gov/pubmed/28682901 http://dx.doi.org/10.1097/MD.0000000000007419 |