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Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection

Influenza A virus (IAV) is a significant cause of life-threatening lower respiratory tract infections in children. Antiviral therapy is the mainstay of treatment, but its effectiveness in this age group has been questioned. In addition, damage inflicted on the lungs by the immune response to the vir...

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Detalles Bibliográficos
Autores principales: Coates, Bria M., Staricha, Kelly L., Ravindran, Nandini, Koch, Clarissa M., Cheng, Yuan, Davis, Jennifer M., Shumaker, Dale K., Ridge, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502347/
https://www.ncbi.nlm.nih.gov/pubmed/28740490
http://dx.doi.org/10.3389/fimmu.2017.00782