Protein recognition by bivalent, ‘turn-on’ fluorescent molecular probes

We show that the conversion of a known intercalating dye (i.e., thiazole orange) into a bivalent protein binder could lead to the realization of a novel class of ‘turn-on’ fluorescent molecular probes that detect proteins with high affinity, selectivity, and a high signal-to-noise (S/N) ratio. The f...

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Detalles Bibliográficos
Autores principales: Unger-Angel, Linor, Rout, Bhimsen, Ilani, Tal, Eisenstein, Miriam, Motiei, Leila, Margulies, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502391/
https://www.ncbi.nlm.nih.gov/pubmed/28717444
http://dx.doi.org/10.1039/c5sc01038a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502391/
https://www.ncbi.nlm.nih.gov/pubmed/28717444
http://dx.doi.org/10.1039/c5sc01038a

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