Recurrent rhinovirus infections in a child with inherited MDA5 deficiency

MDA5 is a cytosolic sensor of double-stranded RNA (ds)RNA including viral byproducts and intermediates. We studied a child with life-threatening, recurrent respiratory tract infections, caused by viruses including human rhinovirus (HRV), influenza virus, and respiratory syncytial virus (RSV). We ide...

Descripción completa

Detalles Bibliográficos
Autores principales: Lamborn, Ian T., Jing, Huie, Zhang, Yu, Drutman, Scott B., Abbott, Jordan K., Munir, Shirin, Bade, Sangeeta, Murdock, Heardley M., Santos, Celia P., Brock, Linda G., Masutani, Evan, Fordjour, Emmanuel Y., McElwee, Joshua J., Hughes, Jason D., Nichols, Dave P., Belkadi, Aziz, Oler, Andrew J., Happel, Corinne S., Matthews, Helen F., Abel, Laurent, Collins, Peter L., Subbarao, Kanta, Gelfand, Erwin W., Ciancanelli, Michael J., Casanova, Jean-Laurent, Su, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502429/
https://www.ncbi.nlm.nih.gov/pubmed/28606988
http://dx.doi.org/10.1084/jem.20161759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502429/
https://www.ncbi.nlm.nih.gov/pubmed/28606988
http://dx.doi.org/10.1084/jem.20161759

Ejemplares similares