Vaccination establishes clonal relatives of germinal center T cells in the blood of humans

Germinal center T follicular helper cells (GCTfh) in lymphatic tissue are critical for B cell differentiation and protective antibody induction, but whether GCTfh establish clonal derivatives as circulating memory T cells is less understood. Here, we used markers expressed on GCTfh, CXCR5, PD1, and...

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Detalles Bibliográficos
Autores principales: Heit, Antje, Schmitz, Frank, Gerdts, Sarah, Flach, Britta, Moore, Miranda S., Perkins, Jonathan A., Robins, Harlan S., Aderem, Alan, Spearman, Paul, Tomaras, Georgia D., De Rosa, Stephen C., McElrath, M. Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502430/
https://www.ncbi.nlm.nih.gov/pubmed/28637884
http://dx.doi.org/10.1084/jem.20161794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502430/
https://www.ncbi.nlm.nih.gov/pubmed/28637884
http://dx.doi.org/10.1084/jem.20161794

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