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Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible

BACKGROUND: Repetitive elements are now known to have relevant cellular functions, including self-complementary sequences that form double stranded (ds) RNA. There are numerous pathways that determine the fate of endogenous dsRNA, and misregulation of endogenous dsRNA is a driver of autoimmune disea...

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Detalles Bibliográficos
Autores principales: McKerrow, Wilson H., Savva, Yiannis A., Rezaei, Ali, Reenan, Robert A., Lawrence, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502491/
https://www.ncbi.nlm.nih.gov/pubmed/28693467
http://dx.doi.org/10.1186/s12864-017-3898-9