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Predicting RNA hyper-editing with a novel tool when unambiguous alignment is impossible
BACKGROUND: Repetitive elements are now known to have relevant cellular functions, including self-complementary sequences that form double stranded (ds) RNA. There are numerous pathways that determine the fate of endogenous dsRNA, and misregulation of endogenous dsRNA is a driver of autoimmune disea...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502491/ https://www.ncbi.nlm.nih.gov/pubmed/28693467 http://dx.doi.org/10.1186/s12864-017-3898-9 |