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Subnanomolar Detection of Oligonucleotides through Templated Fluorogenic Reaction in Hydrogels: Controlling Diffusion to Improve Sensitivity

Oligonucleotide‐templated reactions are valuable tools for nucleic acid sensing both in vitro and in vivo. They are typically carried out under conditions that make any reaction in the absence of template highly unfavorable (most commonly by using a low concentration of reactants), which has a negat...

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Detalles Bibliográficos
Autores principales: Al Sulaiman, Dana, Chang, Jason Y. H., Ladame, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502887/
https://www.ncbi.nlm.nih.gov/pubmed/28382640
http://dx.doi.org/10.1002/anie.201701356