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“Bad Luck Mutations”: DNA Mutations Are not the Whole Answer to Understanding Cancer Risk

It has been proposed that many human cancers are generated by intrinsic mechanisms that produce “Bad Luck” mutations by the proliferation of organ-specific adult stem cells. There have been serious challenges to this interpretation, including multiple extrinsic factors thought to be correlated with...

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Detalles Bibliográficos
Autores principales: Trosko, James E., Carruba, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502948/
https://www.ncbi.nlm.nih.gov/pubmed/28717349
http://dx.doi.org/10.1177/1559325817716585