Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination

BACKGROUND: Merkel cell carcinoma (MCC) is a rare but very aggressive skin tumor that develops after integration of a truncated form of the large T-antigen (truncLT) of the Merkel cell polyomavirus (MCV) into the host’s genome. Therapeutic vaccination with dendritic cells (DCs) loaded with tumor ant...

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Detalles Bibliográficos
Autores principales: Gerer, Kerstin F., Erdmann, Michael, Hadrup, Sine R., Lyngaa, Rikke, Martin, Lena-Marie, Voll, Reinhard E., Schuler-Thurner, Beatrice, Schuler, Gerold, Schaft, Niels, Hoyer, Stefanie, Dörrie, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502952/
https://www.ncbi.nlm.nih.gov/pubmed/28717398
http://dx.doi.org/10.1177/1758834017712630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502952/
https://www.ncbi.nlm.nih.gov/pubmed/28717398
http://dx.doi.org/10.1177/1758834017712630

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