Microwave-Assisted Synthesis of Arene Ru(II) Complexes Induce Tumor Cell Apoptosis Through Selectively Binding and Stabilizing bcl-2 G-Quadruplex DNA

A series of arene Ru(II) complexes coordinated with phenanthroimidazole derivatives, [(η(6)-C(6)H(6))Ru(l)Cl]Cl(1b L = p-ClPIP = 2-(4-Chlorophenyl)imidazole[4,5f] 1,10-phenanthroline; 2b L = m-ClPIP = 2-(3-Chlorophenyl)imidazole[4,5f] 1,10-phenanthroline; 3b L = p-NPIP = 2-(4-Nitrophenyl)imidazole[4...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yanhua, Wu, Qiong, Wang, Xicheng, Xie, Qiang, Tang, Yunyun, Lan, Yutao, Zhang, Shuangyan, Mei, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503023/
https://www.ncbi.nlm.nih.gov/pubmed/28773504
http://dx.doi.org/10.3390/ma9050386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503023/
https://www.ncbi.nlm.nih.gov/pubmed/28773504
http://dx.doi.org/10.3390/ma9050386

Ejemplares similares