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Microwave-Assisted Synthesis of Arene Ru(II) Complexes Induce Tumor Cell Apoptosis Through Selectively Binding and Stabilizing bcl-2 G-Quadruplex DNA

A series of arene Ru(II) complexes coordinated with phenanthroimidazole derivatives, [(η(6)-C(6)H(6))Ru(l)Cl]Cl(1b L = p-ClPIP = 2-(4-Chlorophenyl)imidazole[4,5f] 1,10-phenanthroline; 2b L = m-ClPIP = 2-(3-Chlorophenyl)imidazole[4,5f] 1,10-phenanthroline; 3b L = p-NPIP = 2-(4-Nitrophenyl)imidazole[4...

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Detalles Bibliográficos
Autores principales:	Chen, Yanhua, Wu, Qiong, Wang, Xicheng, Xie, Qiang, Tang, Yunyun, Lan, Yutao, Zhang, Shuangyan, Mei, Wenjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503023/ https://www.ncbi.nlm.nih.gov/pubmed/28773504 http://dx.doi.org/10.3390/ma9050386

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