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Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plants

The recent Zika viral (ZIKV) epidemic has been associated with severe neurological pathologies such as neonatal microcephaly and Guillain-Barre syndrome but unfortunately no vaccine or medication is effectively available yet. Zika NS2B-NS3pro is essential for the proteolysis of the viral polyprotein...

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Detalles Bibliográficos
Autores principales: Roy, Amrita, Lim, Liangzhong, Srivastava, Shagun, Lu, Yimei, Song, Jianxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503262/
https://www.ncbi.nlm.nih.gov/pubmed/28700665
http://dx.doi.org/10.1371/journal.pone.0180632