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Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms
The emergence of influenza drug resistance has become of particular interest as current planning for an influenza pandemic involves using massive amounts of antiviral drugs. We use semi-stochastic simulations to examine the emergence of drug resistant mutants during the course of a single infection...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503263/ https://www.ncbi.nlm.nih.gov/pubmed/28700622 http://dx.doi.org/10.1371/journal.pone.0180582 |