Tumor microenvironment dual-responsive core–shell nanoparticles with hyaluronic acid-shield for efficient co-delivery of doxorubicin and plasmid DNA

As the tumor microenvironment (TME) develops, it is critical to take the alterations of pH value, reduction and various enzymes of the TME into consideration when constructing the desirable co-delivery systems. Herein, TME pH and enzyme dual-responsive core–shell nanoparticles were prepared for the...

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Detalles Bibliográficos
Autores principales: Wang, Tianqi, Yu, Xiaoyue, Han, Leiqiang, Liu, Tingxian, Liu, Yongjun, Zhang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503489/
https://www.ncbi.nlm.nih.gov/pubmed/28740384
http://dx.doi.org/10.2147/IJN.S134378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503489/
https://www.ncbi.nlm.nih.gov/pubmed/28740384
http://dx.doi.org/10.2147/IJN.S134378

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