Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies

The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent melanogenesis inhibitor compared to standard kojic acid. The title amides 4a–e and 6a–e were synthesized...

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Detalles Bibliográficos
Autores principales: Abbas, Qamar, Ashraf, Zaman, Hassan, Mubashir, Nadeem, Humaira, Latif, Muhammad, Afzal, Samina, Seo, Sung-Yum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503496/
https://www.ncbi.nlm.nih.gov/pubmed/28740364
http://dx.doi.org/10.2147/DDDT.S137550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503496/
https://www.ncbi.nlm.nih.gov/pubmed/28740364
http://dx.doi.org/10.2147/DDDT.S137550

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