Organ sculpting by patterned extracellular matrix stiffness

How organ-shaping mechanical imbalances are generated is a central question of morphogenesis, with existing paradigms focusing on asymmetric force generation within cells. We show here that organs can be sculpted instead by patterning anisotropic resistance within their extracellular matrix (ECM). U...

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Detalles Bibliográficos
Autores principales: Crest, Justin, Diz-Muñoz, Alba, Chen, Dong-Yuan, Fletcher, Daniel A, Bilder, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503509/
https://www.ncbi.nlm.nih.gov/pubmed/28653906
http://dx.doi.org/10.7554/eLife.24958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503509/
https://www.ncbi.nlm.nih.gov/pubmed/28653906
http://dx.doi.org/10.7554/eLife.24958

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