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Proximal clustering between BK and Ca(V)1.3 channels promotes functional coupling and BK channel activation at low voltage

Ca(V)-channel dependent activation of BK channels is critical for feedback control of both calcium influx and cell excitability. Here we addressed the functional and spatial interaction between BK and Ca(V)1.3 channels, unique Ca(V)1 channels that activate at low voltages. We found that when BK and...

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Detalles Bibliográficos
Autores principales: Vivas, Oscar, Moreno, Claudia M, Santana, Luis F, Hille, Bertil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503510/
https://www.ncbi.nlm.nih.gov/pubmed/28665272
http://dx.doi.org/10.7554/eLife.28029