The complex of TRIP-Br1 and XIAP ubiquitinates and degrades multiple adenylyl cyclase isoforms

Adenylyl cyclases (ACs) generate cAMP, a second messenger of utmost importance that regulates a vast array of biological processes in all kingdoms of life. However, almost nothing is known about how AC activity is regulated through protein degradation mediated by ubiquitination or other mechanisms....

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Wenbao, Yu, Xiaojie, Liu, Zhengzhao, Sun, Ying, Chen, Xibing, Yang, Xin, Li, Xiaofen, Lam, Wai Kwan, Duan, Yuanyuan, Cao, Xu, Steller, Hermann, Liu, Kai, Huang, Pingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503512/
https://www.ncbi.nlm.nih.gov/pubmed/28656888
http://dx.doi.org/10.7554/eLife.28021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503512/
https://www.ncbi.nlm.nih.gov/pubmed/28656888
http://dx.doi.org/10.7554/eLife.28021

Ejemplares similares