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Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration

CXCL12 has been shown to be involved in colon cancer metastasis, but its expression level and molecular mechanisms regulating its expression remain controversial. We thus evaluated CXCL12 expression in a large cohort of colon adenomas and carcinomas, investigated for an epigenetic mechanism controll...

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Detalles Bibliográficos
Autores principales: Romain, Benoît, Benbrika-Nehmar, Radhia, Marisa, Laetitia, Legrain, Michèle, Lobstein, Viviane, Oravecz, Attila, Poidevin, Laetitia, Bour, Cyril, Freund, Jean-Noël, Duluc, Isabelle, Guenot, Dominique, Pencreach, Erwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503537/
https://www.ncbi.nlm.nih.gov/pubmed/28418886
http://dx.doi.org/10.18632/oncotarget.16323