Synthesis, bioactivity, 3D-QSAR studies of novel dibenzofuran derivatives as PTP-MEG2 inhibitors

PTP-MEG2 plays a critical role in the diverse cell signalling processes, so targeting PTP-MEG2 is a promising strategy for various human diseases treatments. In this study, a series of novel dibenzofuran derivatives was synthesized and assayed for their PTP-MEG2 inhibitory activities. 10a with highe...

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Detalles Bibliográficos
Autores principales: Ma, Ying, Wei, Hui-Yu, Zhang, Yu-Ze, Jin, Wen-Yan, Li, Hong-Lian, Zhou, Hui, Cheng, Xian-Chao, Wang, Run-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503546/
https://www.ncbi.nlm.nih.gov/pubmed/28388567
http://dx.doi.org/10.18632/oncotarget.16595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503546/
https://www.ncbi.nlm.nih.gov/pubmed/28388567
http://dx.doi.org/10.18632/oncotarget.16595

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