CYP genes in osteosarcoma: Their role in tumorigenesis, pulmonary metastatic microenvironment and treatment response

Osteosarcoma (OS) is the most common malignant bone tumor in children and adolescents. The present study investigated the expression of Cytochrome P-450 (CYP) genes: CYP1A2, CYP3A4 and CYP3A5 by qRT-PCR in 135 specimens obtained from OS patients, including biopsy (pre-chemotherapy), tumor resected i...

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Detalles Bibliográficos
Autores principales: Trujillo-Paolillo, Alini, Tesser-Gamba, Francine, Petrilli, Antonio Sergio, de Seixas Alves, Maria Teresa, Filho, Reynaldo Jesus Garcia, de Oliveira, Renato, de Toledo, Silvia Regina Caminada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503551/
https://www.ncbi.nlm.nih.gov/pubmed/28404946
http://dx.doi.org/10.18632/oncotarget.15869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503551/
https://www.ncbi.nlm.nih.gov/pubmed/28404946
http://dx.doi.org/10.18632/oncotarget.15869

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