A mathematical theory of the transcription repression (TR) therapy of cancer – whether and how it may work

Transcription repression (TR) therapy of cancer has been widely discussed. Here, TR refers to global repression of transcription rather than specific targeting of cancer-causing genes such as MYC. TR drugs inhibit transcription by binding to the transcribed DNA or to RNA polymerase; for example, act...

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Detalles Bibliográficos
Autores principales: Chen, Yuxin, Wen, Haijun, Wu, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503560/
https://www.ncbi.nlm.nih.gov/pubmed/28454100
http://dx.doi.org/10.18632/oncotarget.16957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503560/
https://www.ncbi.nlm.nih.gov/pubmed/28454100
http://dx.doi.org/10.18632/oncotarget.16957

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