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A mathematical theory of the transcription repression (TR) therapy of cancer – whether and how it may work
Transcription repression (TR) therapy of cancer has been widely discussed. Here, TR refers to global repression of transcription rather than specific targeting of cancer-causing genes such as MYC. TR drugs inhibit transcription by binding to the transcribed DNA or to RNA polymerase; for example, act...
Autores principales: | Chen, Yuxin, Wen, Haijun, Wu, Chung-I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503560/ https://www.ncbi.nlm.nih.gov/pubmed/28454100 http://dx.doi.org/10.18632/oncotarget.16957 |
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