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A mathematical theory of the transcription repression (TR) therapy of cancer – whether and how it may work

Transcription repression (TR) therapy of cancer has been widely discussed. Here, TR refers to global repression of transcription rather than specific targeting of cancer-causing genes such as MYC. TR drugs inhibit transcription by binding to the transcribed DNA or to RNA polymerase; for example, act...

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Detalles Bibliográficos
Autores principales:	Chen, Yuxin, Wen, Haijun, Wu, Chung-I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503560/ https://www.ncbi.nlm.nih.gov/pubmed/28454100 http://dx.doi.org/10.18632/oncotarget.16957

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