Contributions of MET activation to BCR-ABL1 tyrosine kinase inhibitor resistance in chronic myeloid leukemia cells

Resistance to the breakpoint cluster region-abelson 1 (BCR-ABL1) tyrosine kinase inhibitor (TKI) imatinib poses a major problem when treating chronic myeloid leukemia (CML). Imatinib resistance often results from a secondary mutation in BCR-ABL1. However, in the absence of a mutation in BCR-ABL1, th...

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Detalles Bibliográficos
Autores principales: Tsubaki, Masanobu, Takeda, Tomoya, Kino, Toshiki, Sakai, Kazuko, Itoh, Tatsuki, Imano, Motohiro, Nakayama, Takashi, Nishio, Kazuto, Satou, Takao, Nishida, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503566/
https://www.ncbi.nlm.nih.gov/pubmed/28418880
http://dx.doi.org/10.18632/oncotarget.16314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503566/
https://www.ncbi.nlm.nih.gov/pubmed/28418880
http://dx.doi.org/10.18632/oncotarget.16314

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