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Estrogen enhances mismatch repair by induction of MLH1 expression via estrogen receptor-β

Epidemiological data demonstrated that hormone replace treatment has protective effect against colorectal cancer (CRC). Our previous studies showed that this effect may be associated with DNA mismatch repair. This study aims to investigate the mechanism of estrogen induction of MLH1, and whether col...

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Detalles Bibliográficos
Autores principales: Lu, Jun-Yu, Jin, Peng, Gao, Wei, Wang, De-Zhi, Sheng, Jian-Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503570/
https://www.ncbi.nlm.nih.gov/pubmed/28404976
http://dx.doi.org/10.18632/oncotarget.16351