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Wnt5a and CCL25 promote adult T-cell acute lymphoblastic leukemia cell migration, invasion and metastasis

Adult T-cell acute lymphoblastic leukemia (T-ALL) is a refractory leukemia. We previously showed that CCL25/CCR9 promotes T-ALL metastasis. In the present study, we assessed the effects of CCL25 on Wnt expression and the effects of Wnt5a and CCL25 on PI3K/Akt and RhoA activation. Transwell assays an...

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Detalles Bibliográficos
Autores principales: Deng, Xinzhou, Tu, Zhenbo, Xiong, Meng, Tembo, Kingsley, Zhou, Lu, Liu, Pan, Pan, Shan, Xiong, Jie, Yang, Xiangyong, Leng, Jun, Zhang, Qian, Xiao, Ruijing, Zhang, Qiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503593/
https://www.ncbi.nlm.nih.gov/pubmed/28380463
http://dx.doi.org/10.18632/oncotarget.16559