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Prokaryotic expression of MLAA-34 and generation of a novel human ScFv against MLAA-34 by phage display technology

MLAA-34 is a newly identified monocytic leukemia-associated antigen that is overexpressed in acute monocytic leukemia specifically, thus providing a novel target for the therapy of acute monocytic leukemia. In this study, we first expressed MLAA-34 protein in Escherichia coli (E.coli) BL21 (DE3) cel...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Zhang, Pengyu, He, Aili, Yang, Yun, Wang, Jianli, Zhang, Hui, Zhang, Wanggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503596/
https://www.ncbi.nlm.nih.gov/pubmed/28388565
http://dx.doi.org/10.18632/oncotarget.16590