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Cytochrome P450 1B1 inhibition suppresses tumorigenicity of prostate cancer via caspase-1 activation

Cytochrome P450 1B1 (CYP1B1) is recognized as a universal tumor biomarker and a feasible therapeutic target due to its specific overexpression in cancer tissues. Despite its up-regulation in prostate cancer (PCa), biological significance and clinicopathological features of CYP1B1 are still elusive....

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Detalles Bibliográficos
Autores principales: Chang, Inik, Mitsui, Yozo, Kim, Seul Ki, Sun, Ji Su, Jeon, Hye Sook, Kang, Jung Yun, Kang, Nam Ju, Fukuhara, Shinichiro, Gill, Ankurpreet, Shahryari, Varahram, Tabatabai, Z. Laura, Greene, Kirsten L., Dahiya, Rajvir, Shin, Dong Min, Tanaka, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503597/
https://www.ncbi.nlm.nih.gov/pubmed/28388569
http://dx.doi.org/10.18632/oncotarget.16598