Proton pump inhibitor ilaprazole suppresses cancer growth by targeting T-cell-originated protein kinase

T-cell-originated protein kinase (TOPK) is highly and frequently expressed in various cancer tissues and plays an indispensable role in the mitosis of cancer cells, and therefore, it is an important target for drug treatment of tumor. Ilaprazole was identified to be a potent TOPK inhibitor. The data...

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Detalles Bibliográficos
Autores principales: Zheng, Mengzhu, Luan, Shanshan, Gao, Suyu, Cheng, Li, Hao, Bin, Li, Jiacheng, Chen, Yao, Hou, Xuemei, Chen, Lixia, Li, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503601/
https://www.ncbi.nlm.nih.gov/pubmed/28388576
http://dx.doi.org/10.18632/oncotarget.16609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503601/
https://www.ncbi.nlm.nih.gov/pubmed/28388576
http://dx.doi.org/10.18632/oncotarget.16609

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