IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

Enhanced chemoresistance is, among other factors, believed to be responsible for treatment failure and tumor relapse in patients with epithelial ovarian cancer (EOC). Here, we exposed EOC cells to interleukin-6 (IL-6) to activate oncogenic STAT3, which directly repressed miR-204 via a conserved STAT...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Long, Lulu, Chen, Xiaofang, Feng, Fan, Liu, Yueqin, Zhao, Peiqing, Xu, Yue, Li, Mei, Xu, Wenlin, Li, Yuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503602/
https://www.ncbi.nlm.nih.gov/pubmed/28388577
http://dx.doi.org/10.18632/oncotarget.16610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503602/
https://www.ncbi.nlm.nih.gov/pubmed/28388577
http://dx.doi.org/10.18632/oncotarget.16610

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