Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

Therapeutic antibodies are effective for tumor immunotherapy and exhibit prominent clinical effects. All approved antibody therapeutics utilize IgG as the molecular format. Antibody-dependent cell-mediated cytotoxicity (ADCC) is a key mechanism for tumor cell killing by antibodies. For IgG antibodie...

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Detalles Bibliográficos
Autores principales: Li, Bingyu, Xu, Lijun, Tao, Fei, Xie, Kun, Wu, Zhiqiang, Li, You, Li, Jie, Chen, Kaiming, Pi, Chenyu, Mendelsohn, Andrew, Larrick, James W., Gu, Hua, Fang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503618/
https://www.ncbi.nlm.nih.gov/pubmed/28454118
http://dx.doi.org/10.18632/oncotarget.17000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503618/
https://www.ncbi.nlm.nih.gov/pubmed/28454118
http://dx.doi.org/10.18632/oncotarget.17000

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