Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer

Dickkopf-related protein 2 (DKK2) is one of the antagonists of Wnt/β-catenin signaling, with its downregulation reported in multiple cancers. However, how DKK2 contributes to breast tumorigenesis remains unclear. We examined its expression and promoter methylation in 10 breast tumor cell lines, 98 p...

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Detalles Bibliográficos
Autores principales: Mu, Junhao, Hui, Tianli, Shao, Bianfei, Li, Lili, Du, Zhenfang, Lu, Li, Ye, Lin, Li, Shuman, Li, Qianqian, Xiao, Qian, Qiu, Zhu, Zhang, Yan, Fan, Jiangxia, Ren, Guosheng, Tao, Qian, Xiang, Tingxiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503624/
https://www.ncbi.nlm.nih.gov/pubmed/28467796
http://dx.doi.org/10.18632/oncotarget.17055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503624/
https://www.ncbi.nlm.nih.gov/pubmed/28467796
http://dx.doi.org/10.18632/oncotarget.17055

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