A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

SPiDER-βGal is a newly-developed probe that is activated by β-galactosidase and is then retained within cells by anchoring to intracellular proteins. Previous work has focused on gGlu-HMRG, a probe activated by γ-glutamyltranspeptidase, which demonstrated high sensitivity for the detection of perito...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Yuko, Mochida, Ai, Nagaya, Tadanobu, Okuyama, Shuhei, Ogata, Fusa, Choyke, Peter L., Kobayashi, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503628/
https://www.ncbi.nlm.nih.gov/pubmed/28467810
http://dx.doi.org/10.18632/oncotarget.17080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503628/
https://www.ncbi.nlm.nih.gov/pubmed/28467810
http://dx.doi.org/10.18632/oncotarget.17080

Ejemplares similares