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A topically-sprayable, activatable fluorescent and retaining probe, SPiDER-βGal for detecting cancer: Advantages of anchoring to cellular proteins after activation

SPiDER-βGal is a newly-developed probe that is activated by β-galactosidase and is then retained within cells by anchoring to intracellular proteins. Previous work has focused on gGlu-HMRG, a probe activated by γ-glutamyltranspeptidase, which demonstrated high sensitivity for the detection of perito...

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Detalles Bibliográficos
Autores principales:	Nakamura, Yuko, Mochida, Ai, Nagaya, Tadanobu, Okuyama, Shuhei, Ogata, Fusa, Choyke, Peter L., Kobayashi, Hisataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503628/ https://www.ncbi.nlm.nih.gov/pubmed/28467810 http://dx.doi.org/10.18632/oncotarget.17080

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