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Genetic rearrangements result in altered gene expression and novel fusion transcripts in Sézary syndrome

Sézary syndrome (SS) is an aggressive, leukemic cutaneous T-cell lymphoma variant. Molecular pathogenesis of SS is still unclear despite many studies on genetic alterations, gene expression and epigenetic regulations. Through whole genome and transcriptome next generation sequencing nine Sézary synd...

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Detalles Bibliográficos
Autores principales: Przybylski, Grzegorz K., Gand, Claudia, Braun, Floriane C., Grabarczyk, Piotr, Kuss, Andreas W., Olek-Hrab, Karolina, Bastidas Torres, Armando N., Vermeer, Maarten H., Zoutman, Willem H., Tensen, Cornelis P., Schmidt, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503638/
https://www.ncbi.nlm.nih.gov/pubmed/28489605
http://dx.doi.org/10.18632/oncotarget.17383