Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis

Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6G(high)CD11b(+)) and immature (Ly6G(low)CD11b(+)) neutrophil...

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Detalles Bibliográficos
Autores principales: Sánchez, Ángela, Relaño, Carlos, Carrasco, Araceli, Contreras-Jurado, Constanza, Martín-Duce, Antonio, Aranda, Ana, Alemany, Susana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503936/
https://www.ncbi.nlm.nih.gov/pubmed/28694430
http://dx.doi.org/10.1038/s41598-017-04538-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503936/
https://www.ncbi.nlm.nih.gov/pubmed/28694430
http://dx.doi.org/10.1038/s41598-017-04538-3

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