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Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting

Complement protein C3 is the pivotal component of the complement system. Previous studies have demonstrated that C3 has implications in various human diseases and exerts profound functions under certain conditions. However, the delineation of pathological and physiological roles of C3 has been hampe...

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Detalles Bibliográficos
Autores principales:	Zhang, Wei, Wang, Guan, Wang, Ying, Jin, Yong, Zhao, Lihua, Xiong, Qiang, Zhang, Lining, Mou, Lisha, Li, Rongfeng, Yang, Haiyuan, Dai, Yifan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503937/ https://www.ncbi.nlm.nih.gov/pubmed/28694465 http://dx.doi.org/10.1038/s41598-017-05400-2

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