Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice

The current study evaluated the role of Hey2 transcription factor in radiation-induced endothelial-to-mesenchymal transition (EndoMT) and its impact on radiation-induced tissue damage in mice. Phenotypic modifications of irradiated, Hey2 siRNA- and Hey2 vector plasmid-transfected human umbilical vei...

Descripción completa

Detalles Bibliográficos
Autores principales: Mintet, Elodie, Lavigne, Jérémy, Paget, Vincent, Tarlet, Georges, Buard, Valérie, Guipaud, Olivier, Sabourin, Jean-Christophe, Iruela-Arispe, Maria-Luisa, Milliat, Fabien, François, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503994/
https://www.ncbi.nlm.nih.gov/pubmed/28694461
http://dx.doi.org/10.1038/s41598-017-05389-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503994/
https://www.ncbi.nlm.nih.gov/pubmed/28694461
http://dx.doi.org/10.1038/s41598-017-05389-8

Ejemplares similares