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Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer’s disease brains

Gadolinium (Gd)-stained MRI is based on Gd contrast agent (CA) administration into the brain parenchyma. The strong signal increase induced by Gd CA can be converted into resolution enhancement to record microscopic MR images. Moreover, inhomogeneous distribution of the Gd CA in the brain improves t...

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Detalles Bibliográficos
Autores principales: Dudeffant, Clémence, Vandesquille, Matthias, Herbert, Kelly, Garin, Clément M., Alves, Sandro, Blanchard, Véronique, Comoy, Emmanuel E., Petit, Fanny, Dhenain, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504006/
https://www.ncbi.nlm.nih.gov/pubmed/28694463
http://dx.doi.org/10.1038/s41598-017-05285-1