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Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer’s disease brains
Gadolinium (Gd)-stained MRI is based on Gd contrast agent (CA) administration into the brain parenchyma. The strong signal increase induced by Gd CA can be converted into resolution enhancement to record microscopic MR images. Moreover, inhomogeneous distribution of the Gd CA in the brain improves t...
Autores principales: | Dudeffant, Clémence, Vandesquille, Matthias, Herbert, Kelly, Garin, Clément M., Alves, Sandro, Blanchard, Véronique, Comoy, Emmanuel E., Petit, Fanny, Dhenain, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504006/ https://www.ncbi.nlm.nih.gov/pubmed/28694463 http://dx.doi.org/10.1038/s41598-017-05285-1 |
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