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Functional determinants of protein assembly into homomeric complexes

Approximately half of proteins with experimentally determined structures can interact with other copies of themselves and assemble into homomeric complexes, the overwhelming majority of which (>96%) are symmetric. Although homomerisation is often assumed to a functionally beneficial result of evo...

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Detalles Bibliográficos
Autores principales: Bergendahl, L. Therese, Marsh, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504011/
https://www.ncbi.nlm.nih.gov/pubmed/28694495
http://dx.doi.org/10.1038/s41598-017-05084-8