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Presence of diabetes autoantigens in extracellular vesicles derived from human islets

Beta-cell (β-cell) injury is the hallmark of autoimmune diabetes. However, the mechanisms by which autoreactive responses are generated in susceptible individuals are not well understood. Extracellular vesicles (EV) are produced by mammalian cells under normal and stressed physiological states. They...

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Detalles Bibliográficos
Autores principales: Hasilo, Craig P., Negi, Sarita, Allaeys, Isabelle, Cloutier, Nathalie, Rutman, Alissa K., Gasparrini, Marco, Bonneil, Éric, Thibault, Pierre, Boilard, Éric, Paraskevas, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504025/
https://www.ncbi.nlm.nih.gov/pubmed/28694505
http://dx.doi.org/10.1038/s41598-017-04977-y